• Predictive framework for codend size selection of brown shrimp (Crangon crangon) in the North Sea beam-trawl fishery 

      Santos, Juan; Herrmann, Bent; Stepputtis, Daniel; Gunther, Claudia; Limmer, Bente; Mieske, Bernd; Schultz, Sebastian; Neudecker, Thomas; Temming, Axel; Hufnagl, Marc; Bethke, Eckhard; Kraus, Gerd (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-16)
      The brown shrimp (<i>Crangon crangon</i>) fishery is of great socio-economic importance to coastal communities on the North Sea. The fishery is exploited by beam trawlers often using codends with very small mesh sizes, leading to concerns about catch rates of undersized shrimp. However, little information is available on codend size selection, making it difficult to provide scientifically based ...
    • Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake 

      Jakobi, Arjen J.; Huber, Stefan T.; Mortensen, Simon A.; Schultz, Sebastian; Palara, Anthimi; Kuhm, Tanja; Shrestha, Birendra Kumar; Lamark, Trond; Hagen, Wim J.H.; Wilmanns, Matthias; Johansen, Terje; Brech, Andreas; Sachse, Carsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-23)
      p62/SQSTM1 is an autophagy receptor and signaling adaptor with an N-terminal PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The molecular determinants that govern PB1 domain filament formation in vitro remain to be determined and the role of p62 filaments inside the cell is currently unclear. We here determine four high-resolution cryo-EM structures of different human ...